Opioids: keeping the good, eliminating the bad

The Good , The Bad , and The Ugly

Electronic mail has become the unexciting and mundane electronic communication medium we love to hate. It wasn’t always that way. Hate is a fairly recent emotion. Email has been with us in one form or another since the earliest days of computer networks and bulletin board services. From inauspicious beginnings, it became one of the three “killer apps,” along with Telnet and FTP, that gave the I...

The Good, the Bad and the Ugly

This paper discusses the neo-logicist approach to the foundations of mathematics by highlighting an issue that arises from looking at the Bad Company objection from an epistemological perspective. For the most part, our issue is independent of the details of any resolution of the Bad Company objection and, as we will show, it concerns other foundational approaches in the philosophy of mathemati...

The good, the bad and the median.

I don’t write so many editorials because, like all group leaders, I am busy trying to get my lab’s research published to help my people’s careers, get grants and even keep my own job. Obviously, the best way to do that is to ensure the papers appear in the best journal possible. You know, those with the highest impact factor, that simple number that says so much about the ‘quality’ of the scien...

[The good, the bad, the ugly?].

The Good, the Bad, and the Ugly

During the last several years, we have witnessed “the best of times and the worst of times” in the embryonic field of gene therapy. Rapid advances in human genomic sciences, the development of novel mouse models of human diseases, and the construction and characterization of new vector systems for in vivo gene transduction have significantly expanded the potential feasibility of human gene ther...